In 1966, After a truck accident sends a nasty cocktail of hundreds of gallons of multiple pathogens into the groundwater of a small California town, the virus brings out the worst in the townspeople, as they slowly become more and more belligerent, arrogant, mutated, and violent during the last weekend before Christmas.
After the weekend culminates in extreme violence and over-the-top mayhem, a Liberal reporter realizes that her education and virtue signalling alone won't be enough to live through the night, if she wants to find out who is behind the conspiracy to weaponize impressionable idiots and destroy Western civilization.